sof 700ra 25 two chamber place preference apparatus Search Results


conditioning chamber  (Med Associates Inc)
97
Med Associates Inc conditioning chamber
Figure 5. Contextual and cued fear <t>conditioning.</t> Males: B6 OT, n = 8; B6 saline, n = 11; BTBR OT, n = 11; BTBR saline, n = 12. Females: B6 OT, n = 10; B6 saline, n = 12; BTBR OT, n = 10; BTBR saline, n = 12. (a and b) Both strains froze similarly in response to the unconditioned stimulus (all Po0.0001). (c and d) BTBR mice froze significantly less during the contextual cues session (all Po0.0001). (e and f) Although both strains displayed freezing to the auditory cue (all Po0.0001), BTBR froze less than B6, showing a significant strain and strain by cue interaction (Po0.0001). OT, oxytocin.
Conditioning Chamber, supplied by Med Associates Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/conditioning chamber/product/Med Associates Inc
Average 97 stars, based on 1 article reviews
conditioning chamber - by Bioz Stars, 2026-03
97/100 stars
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place conditioning apparatus  (Med Associates Inc)
96
Med Associates Inc place conditioning apparatus
Effects of high and low doses of BDNF on 5 and 15 mg/kg morphine-conditioned place preferences in mice. a, Infusions of 0.025 μg BDNF (same dose used in rats by Vargas-Perez et al. (2009b)) or 0.25 μg BDNF (dose used by Koo et al. (2012)) in mouse VTA did not abolish 5 mg/kg morphine place preferences, but resulted in a switch to a DA-dependent motivational state wherein α-flupenthixol blocks the conditioned place preferences. b, Infusions of 0.25 μg BDNF in mouse VTA did not abolish 15 mg/kg morphine-conditioned place preferences, even when the duration of <t>conditioning</t> sessions was extended to 45 min to match the conditions used by Koo et al. (2009). c, Infusions of 0.25 μg BDNF in mouse VTA did not abolish 15 mg/kg morphine preferences even after using the same conditioned place preference paradigm and VTA coordinates used by Koo et al. (2012); *p values <0.05.
Place Conditioning Apparatus, supplied by Med Associates Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/place conditioning apparatus/product/Med Associates Inc
Average 96 stars, based on 1 article reviews
place conditioning apparatus - by Bioz Stars, 2026-03
96/100 stars
  Buy from Supplier

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Figure 5. Contextual and cued fear conditioning. Males: B6 OT, n = 8; B6 saline, n = 11; BTBR OT, n = 11; BTBR saline, n = 12. Females: B6 OT, n = 10; B6 saline, n = 12; BTBR OT, n = 10; BTBR saline, n = 12. (a and b) Both strains froze similarly in response to the unconditioned stimulus (all Po0.0001). (c and d) BTBR mice froze significantly less during the contextual cues session (all Po0.0001). (e and f) Although both strains displayed freezing to the auditory cue (all Po0.0001), BTBR froze less than B6, showing a significant strain and strain by cue interaction (Po0.0001). OT, oxytocin.

Journal: Translational psychiatry

Article Title: Long-term exposure to intranasal oxytocin in a mouse autism model.

doi: 10.1038/tp.2014.117

Figure Lengend Snippet: Figure 5. Contextual and cued fear conditioning. Males: B6 OT, n = 8; B6 saline, n = 11; BTBR OT, n = 11; BTBR saline, n = 12. Females: B6 OT, n = 10; B6 saline, n = 12; BTBR OT, n = 10; BTBR saline, n = 12. (a and b) Both strains froze similarly in response to the unconditioned stimulus (all Po0.0001). (c and d) BTBR mice froze significantly less during the contextual cues session (all Po0.0001). (e and f) Although both strains displayed freezing to the auditory cue (all Po0.0001), BTBR froze less than B6, showing a significant strain and strain by cue interaction (Po0.0001). OT, oxytocin.

Article Snippet: Fear conditioning Delay contextual and cued fear conditioning was conducted using an automated fear-conditioning chamber (Med Associates, St Albans, VT, USA) as previously described.72 The conditioning chamber (32 × 25 × 23 cm3, Med Associates) was interfaced to a PC installed with VideoFreeze software (version 1.12.0.0, Med Associates) and enclosed in a sound-attenuating cubicle.

Techniques: Saline

Effects of high and low doses of BDNF on 5 and 15 mg/kg morphine-conditioned place preferences in mice. a, Infusions of 0.025 μg BDNF (same dose used in rats by Vargas-Perez et al. (2009b)) or 0.25 μg BDNF (dose used by Koo et al. (2012)) in mouse VTA did not abolish 5 mg/kg morphine place preferences, but resulted in a switch to a DA-dependent motivational state wherein α-flupenthixol blocks the conditioned place preferences. b, Infusions of 0.25 μg BDNF in mouse VTA did not abolish 15 mg/kg morphine-conditioned place preferences, even when the duration of conditioning sessions was extended to 45 min to match the conditions used by Koo et al. (2009). c, Infusions of 0.25 μg BDNF in mouse VTA did not abolish 15 mg/kg morphine preferences even after using the same conditioned place preference paradigm and VTA coordinates used by Koo et al. (2012); *p values <0.05.

Journal: The Journal of Neuroscience

Article Title: BDNF Signaling in the VTA Links the Drug-Dependent State to Drug Withdrawal Aversions

doi: 10.1523/JNEUROSCI.3776-13.2014

Figure Lengend Snippet: Effects of high and low doses of BDNF on 5 and 15 mg/kg morphine-conditioned place preferences in mice. a, Infusions of 0.025 μg BDNF (same dose used in rats by Vargas-Perez et al. (2009b)) or 0.25 μg BDNF (dose used by Koo et al. (2012)) in mouse VTA did not abolish 5 mg/kg morphine place preferences, but resulted in a switch to a DA-dependent motivational state wherein α-flupenthixol blocks the conditioned place preferences. b, Infusions of 0.25 μg BDNF in mouse VTA did not abolish 15 mg/kg morphine-conditioned place preferences, even when the duration of conditioning sessions was extended to 45 min to match the conditions used by Koo et al. (2009). c, Infusions of 0.25 μg BDNF in mouse VTA did not abolish 15 mg/kg morphine preferences even after using the same conditioned place preference paradigm and VTA coordinates used by Koo et al. (2012); *p values <0.05.

Article Snippet: The place conditioning apparatus (Med-Associates SOF-700RA-25) used consisted of a black compartment with metal rod floor, a white compartment with a wire mesh floor, and a gray compartment in the middle that contained a partition on both sides.

Techniques: Conditioned Place Preference

Motivational effects of withdrawal in opiate-dependent animals after blocking BDNF function in the VTA. a, Knocking down TrkB in the VTA with LV-siRNAs did not affect spontaneous opiate somatic withdrawal signs. Both LV-siRNAs (n = 8) and LV-GFP (n = 8) animals show an increase in percentage abstinence scores over time after 16 h heroin administration with respect to saline control animals (n = 8; *p < 0.05). b, Opiate naive (n = 7) and dependent (n = 7) LV-siRNAs-treated animals display a reduction in low-frequency (22 kHz) s compared with opiate naive (n = 7) and dependent (n = 7) LV-GFP-treated animals (*p < 0.05) during naloxone-precipitated chronic opiate withdrawal during the course of a 10 min test session. c, Knocking down TrkB in the VTA with LV-siRNAs blocks the place aversion for 16 h of abstinence from morphine (3 mg/kg) in dependent rats (n = 8). In contrast, control opiate-dependent animals infected with LV-GFP (n = 8) show conditioned place aversions (*p < 0.05). d, Naloxone-conditioned (5 mg/kg) place aversions were blocked in LV-siRNAs-treated (n = 8) dependent animals, but not in LV-GFP-treated (n = 8) animals (*p < 0.05). e, Both LV-siRNAs (n = 8) and LV-GFP (n = 8)-infected animals display a conditioning place aversion to LiCl (5 mg/kg; *p < 0.05). Data represent the means ± SEM the absolute times spent in the previously saline and previously drug paired compartments.

Journal: The Journal of Neuroscience

Article Title: BDNF Signaling in the VTA Links the Drug-Dependent State to Drug Withdrawal Aversions

doi: 10.1523/JNEUROSCI.3776-13.2014

Figure Lengend Snippet: Motivational effects of withdrawal in opiate-dependent animals after blocking BDNF function in the VTA. a, Knocking down TrkB in the VTA with LV-siRNAs did not affect spontaneous opiate somatic withdrawal signs. Both LV-siRNAs (n = 8) and LV-GFP (n = 8) animals show an increase in percentage abstinence scores over time after 16 h heroin administration with respect to saline control animals (n = 8; *p < 0.05). b, Opiate naive (n = 7) and dependent (n = 7) LV-siRNAs-treated animals display a reduction in low-frequency (22 kHz) s compared with opiate naive (n = 7) and dependent (n = 7) LV-GFP-treated animals (*p < 0.05) during naloxone-precipitated chronic opiate withdrawal during the course of a 10 min test session. c, Knocking down TrkB in the VTA with LV-siRNAs blocks the place aversion for 16 h of abstinence from morphine (3 mg/kg) in dependent rats (n = 8). In contrast, control opiate-dependent animals infected with LV-GFP (n = 8) show conditioned place aversions (*p < 0.05). d, Naloxone-conditioned (5 mg/kg) place aversions were blocked in LV-siRNAs-treated (n = 8) dependent animals, but not in LV-GFP-treated (n = 8) animals (*p < 0.05). e, Both LV-siRNAs (n = 8) and LV-GFP (n = 8)-infected animals display a conditioning place aversion to LiCl (5 mg/kg; *p < 0.05). Data represent the means ± SEM the absolute times spent in the previously saline and previously drug paired compartments.

Article Snippet: The place conditioning apparatus (Med-Associates SOF-700RA-25) used consisted of a black compartment with metal rod floor, a white compartment with a wire mesh floor, and a gray compartment in the middle that contained a partition on both sides.

Techniques: Blocking Assay, Saline, Control, Infection